Many efforts have been made to construct dialog systems for different types of conversations, such as task-oriented dialog (TOD) and open-domain dialog (ODD). To better mimic human-level conversations that usually fuse various dialog modes, it is essential to build a system that can effectively handle both TOD and ODD and access different knowledge sources. To address the lack of available data for the fused task, we propose a framework for automatically generating dialogues that combine knowledge-grounded ODDs and TODs in various settings. Additionally, we introduce a unified model PivotBot that is capable of appropriately adopting TOD and ODD modes and accessing different knowledge sources in order to effectively tackle the fused task. Evaluation results demonstrate the superior ability of the proposed model to switch seamlessly between TOD and ODD tasks.

Recent advances in generative adversarial networks (GANs) have demonstrated the capabilities of generating stunning photo-realistic portrait images. While some prior works have applied such image GANs to unconditional 2D portrait video generation and static 3D portrait synthesis, there are few works successfully extending GANs for generating 3D-aware portrait videos. In this work, we propose PV3D, the first generative framework that can synthesize multi-view consistent portrait videos. Specifically, our method extends the recent static 3D-aware image GAN to the video domain by generalizing the 3D implicit neural representation to model the spatio-temporal space. To introduce motion dynamics to the generation process, we develop a motion generator by stacking multiple motion layers to generate motion features via modulated convolution. To alleviate motion ambiguities caused by camera/human motions, we propose a simple yet effective camera condition strategy for PV3D, enabling both temporal and multi-view consistent video generation. Moreover, PV3D introduces two discriminators for regularizing the spatial and temporal domains to ensure the plausibility of the generated portrait videos. These elaborated designs enable PV3D to generate 3D-aware motion-plausible portrait videos with high-quality appearance and geometry, significantly outperforming prior works. As a result, PV3D is able to support many downstream applications such as animating static portraits and view-consistent video motion editing. Code and models will be released at https://showlab.github.io/pv3d.

Automatic parsing of human anatomies at instance-level from 3D computed tomography (CT) scans is a prerequisite step for many clinical applications. The presence of pathologies, broken structures or limited field-of-view (FOV) all can make anatomy parsing algorithms vulnerable. In this work, we explore how to exploit and conduct the prosperous detection-then-segmentation paradigm in 3D medical data, and propose a steerable, robust, and efficient computing framework for detection, identification, and segmentation of anatomies in CT scans. Considering complicated shapes, sizes and orientations of anatomies, without lose of generality, we present the nine degrees-of-freedom (9-DoF) pose estimation solution in full 3D space using a novel single-stage, non-hierarchical forward representation. Our whole framework is executed in a steerable manner where any anatomy of interest can be directly retrieved to further boost the inference efficiency. We have validated the proposed method on three medical imaging parsing tasks of ribs, spine, and abdominal organs. For rib parsing, CT scans have been annotated at the rib instance-level for quantitative evaluation, similarly for spine vertebrae and abdominal organs. Extensive experiments on 9-DoF box detection and rib instance segmentation demonstrate the effectiveness of our framework (with the identification rate of 97.0% and the segmentation Dice score of 90.9%) in high efficiency, compared favorably against several strong baselines (e.g., CenterNet, FCOS, and nnU-Net). For spine identification and segmentation, our method achieves a new state-of-the-art result on the public CTSpine1K dataset. Last, we report highly competitive results in multi-organ segmentation at FLARE22 competition. Our annotations, code and models will be made publicly available at: https://github.com/alibaba-damo-academy/Med_Query.

Segmenting the fine structure of the mouse brain on magnetic resonance (MR) images is critical for delineating morphological regions, analyzing brain function, and understanding their relationships. Compared to a single MRI modality, multimodal MRI data provide complementary tissue features that can be exploited by deep learning models, resulting in better segmentation results. However, multimodal mouse brain MRI data is often lacking, making automatic segmentation of mouse brain fine structure a very challenging task. To address this issue, it is necessary to fuse multimodal MRI data to produce distinguished contrasts in different brain structures. Hence, we propose a novel disentangled and contrastive GAN-based framework, named MouseGAN++, to synthesize multiple MR modalities from single ones in a structure-preserving manner, thus improving the segmentation performance by imputing missing modalities and multi-modality fusion. Our results demonstrate that the translation performance of our method outperforms the state-of-the-art methods. Using the subsequently learned modality-invariant information as well as the modality-translated images, MouseGAN++ can segment fine brain structures with averaged dice coefficients of 90.0% (T2w) and 87.9% (T1w), respectively, achieving around +10% performance improvement compared to the state-of-the-art algorithms. Our results demonstrate that MouseGAN++, as a simultaneous image synthesis and segmentation method, can be used to fuse cross-modality information in an unpaired manner and yield more robust performance in the absence of multimodal data. We release our method as a mouse brain structural segmentation tool for free academic usage at https://github.com/yu02019.

Diverse data formats and ontologies of task-oriented dialogue (TOD) datasets hinder us from developing general dialogue models that perform well on many datasets and studying knowledge transfer between datasets. To address this issue, we present ConvLab-3, a flexible dialogue system toolkit based on a unified TOD data format. In ConvLab-3, different datasets are transformed into one unified format and loaded by models in the same way. As a result, the cost of adapting a new model or dataset is significantly reduced. Compared to the previous releases of ConvLab (Lee et al., 2019b; Zhu et al., 2020b), ConvLab-3 allows developing dialogue systems with much more datasets and enhances the utility of the reinforcement learning (RL) toolkit for dialogue policies. To showcase the use of ConvLab-3 and inspire future work, we present a comprehensive study with various settings. We show the benefit of pre-training on other datasets for few-shot fine-tuning and RL, and encourage evaluating policy with diverse user simulators.

The image captioning task is typically realized by an auto-regressive method that decodes the text tokens one by one. We present a diffusion-based captioning model, dubbed the name DDCap, to allow more decoding flexibility. Unlike image generation, where the output is continuous and redundant with a fixed length, texts in image captions are categorical and short with varied lengths. Therefore, naively applying the discrete diffusion model to text decoding does not work well, as shown in our experiments. To address the performance gap, we propose several key techniques including best-first inference, concentrated attention mask, text length prediction, and image-free training. On COCO without additional caption pre-training, it achieves a CIDEr score of 117.8, which is +5.0 higher than the auto-regressive baseline with the same architecture in the controlled setting. It also performs +26.8 higher CIDEr score than the auto-regressive baseline (230.3 v.s.203.5) on a caption infilling task. With 4M vision-language pre-training images and the base-sized model, we reach a CIDEr score of 125.1 on COCO, which is competitive to the best well-developed auto-regressive frameworks. The code is available at https://github.com/buxiangzhiren/DDCap.

我们为指定实体识别（NER）提出了一个有效的双重编码框架，该框架将对比度学习用于映射候选文本跨度，并将实体类型映射到同一矢量表示空间中。先前的工作主要将NER作为序列标记或跨度分类。相反，我们将NER视为一个度量学习问题，它最大程度地提高了实体提及的向量表示之间的相似性及其类型。这使得易于处理嵌套和平坦的ner，并且可以更好地利用嘈杂的自我诉讼信号。 NER对本双重编码器制定的主要挑战在于将非实体跨度与实体提及分开。我们没有明确标记所有非实体跨度为外部（O）与大多数先前方法相同的类别（O），而是引入了一种新型的动态阈值损失，这与标准的对比度损失一起学习。实验表明，我们的方法在受到监督和远处有监督的设置中的表现良好（例如，Genia，NCBI，BC5CDR，JNLPBA）。

尽管最近在跨模式检索领域取得了进展，但由于缺乏手动注释的数据集，研究的重点较少。在本文中，我们提出了一种用于低资源语言的噪声跨语法跨模式检索方法。为此，我们使用机器翻译（MT）来构建低资源语言的伪并行句子对。但是，由于MT并不完美，因此它倾向于在翻译过程中引入噪音，从而使文本嵌入被损坏，从而损害了检索性能。为了减轻这一点，我们引入了一种多视图自我验证方法来学习噪声稳定目标语言表示，该方法采用了跨注意模块来生成软伪靶标，以从基于相似性的视图和功能 - 功能 - 基于视图。此外，受到无监督的MT的反向翻译的启发，我们最大程度地减少了原点句子和反翻译句子之间的语义差异，以进一步提高文本编码器的噪声稳健性。在三个视频文本和图像文本跨模式检索基准跨不同语言上进行了广泛的实验，结果表明，我们的方法显着改善了整体性能，而无需使用额外的人体标记数据。此外，从最近的视觉和语言预训练框架（即剪辑）中配备了预训练的视觉编码器，我们的模型可实现显着的性能增长，这表明我们的方法与流行的预训练模型兼容。代码和数据可在https://github.com/huiguanlab/nrccr上找到。

当前的文本到视频检索方法（T2VR）经过培训和测试，并在视频捕获方向的数据集（例如MSVD，MSR-VTT和VATEX）上进行了测试。这些数据集的一个关键属性是，假定视频在短时间内被暂时预先修剪，而提供的字幕很好地描述了视频内容的要旨。因此，对于给定的配对视频和标题，该视频应该与标题完全相关。但是，实际上，由于查询尚不清楚，因此预处理的视频剪辑可能不包含足够的内容来完全满足查询。这表明文学与现实世界之间存在差距。为了填补空白，我们在本文中提出了一个新颖的T2VR子任务，称为部分相关的视频检索（PRVR）。未修剪的视频被认为是部分相关的W.R.T.给定的文本查询是否包含与查询相关的时刻。 PRVR旨在从大量未修剪视频中检索此类相关视频。 PRVR与单个视频时刻检索和视频语料库时刻的检索有所不同，因为后两个是要检索时刻而不是未修剪的视频。我们将PRVR作为多个实例学习（MIL）问题，同时将视频视为一袋视频片段和一袋视频帧。剪辑和帧表示不同时间尺度的视频内容。我们提出了一个多尺度的相似性学习（MS-SL）网络，该网络共同学习PRVR的剪辑规模和框架尺度相似性。在三个数据集（TVR，ActivityNet字幕和Charades-STA）上进行了广泛的实验，证明了该方法的可行性。我们还表明，我们的方法可用于改善视频语料库时刻的检索。

由于复杂的腹部内形状和腹部器官之间的复杂形状和外观变化，从不同模态的CT成像中进行的准确且健壮的腹部多器官分割是一项具有挑战性的任务。在本文中，我们提出了一个具有分层空间特征调制的概率多器官分割网络，以捕获灵活的器官语义变体，并将学习的变体注入不同的特征图尺度，以进行指导分割。更具体地说，我们通过条件变异自动编码器设计一个输入分解模块，以在低维潜在空间和模型富有器官语义变化上学习器官特异性分布，该分布在输入图像上进行条件。 -NET解码器通过空间特征转换从层次上进行分层，该特征转换能够将变化转换为空间特征映射调制并指导细尺度分割的条件仿射转换参数。提出的方法对公开可用的腹部可用数据集进行了培训，并在其他两个开放数据集上进行了评估，即100个挑战/病理测试，从腹部腹部1K完全监督的腹部器官细分基准和90例TCIA+＆BTCV数据集中进行了90例病例。使用这些数据集用于四个腹部器官，肾脏，脾脏和胰腺，肾脏分数提高了7.3％，胰腺的骰子得分提高了7.7％，而胰腺的骰子得分提高了7.3％，而胰腺的较高速度比强度快7倍，较高的7倍基线分割方法（NNUNET和COTR）。